Last update
5/9/2025
Research Authors

Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Medium or Average
Based on 6 Reviews
6.9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
667 mcg DFE (400 mcg Folic Acid)
167%
Calcium (as Calcium Carbonate)
100 mg
8%

Top Medical Research Studies

9
Folic acid nanomedicine alleviates pain
We explored an innovative treatment for chronic bacterial prostatitis (CBP) by creating antibiotic-loaded nanoparticles modified with folic acid. These nanoparticles can effectively target and penetrate the prostate tissues where inflammation and pain occur.

In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
Read More
We examined the effects of Flower pollen extract with vitamins (Deprox 500®) on chronic pelvic pain compared to Serenoa repens in patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).

In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.

Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
Read More

Most Useful Reviews

9
Pelvic pain relief
After one month of taking the drug, my pelvic pain during menstruation disappeared. I occasionally take courses to maintain this benefit.
Read More
9
Significant pain reduction
Folic acid has notably reduced my pelvic pain and PMS symptoms. My mood is more stable, and my skin, hair, and nails have improved. I recommend it to everyone, including men, for its various benefits.
Read More
2
Minimal effectiveness
2 people found this helpful
I bought it to help with my pelvic pain, but I did not notice much effect.
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
  • All Researches
9
Folic acid nanomedicine alleviates pain
We explored an innovative treatment for chronic bacterial prostatitis (CBP) by creating antibiotic-loaded nanoparticles modified with folic acid. These nanoparticles can effectively target and penetrate the prostate tissues where inflammation and pain occur.

In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.
Read More
We examined the effects of Flower pollen extract with vitamins (Deprox 500®) on chronic pelvic pain compared to Serenoa repens in patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).

In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.

Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
Read More

User Reviews

USERS' SCORE
Medium or Average
Based on 6 Reviews
6.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Pelvic pain relief
After one month of taking the drug, my pelvic pain during menstruation disappeared. I occasionally take courses to maintain this benefit.
Read More
9
Significant pain reduction
Folic acid has notably reduced my pelvic pain and PMS symptoms. My mood is more stable, and my skin, hair, and nails have improved. I recommend it to everyone, including men, for its various benefits.
Read More
2
Minimal effectiveness
2 people found this helpful
I bought it to help with my pelvic pain, but I did not notice much effect.
Read More
4
Caused abdominal pain
After a couple of days, I experienced pelvic pain, so I stopped taking it, and the pain went away.
Read More
2
Causes discomfort
It's better to take folate instead, as this form induces pelvic pain.
Read More

Frequently Asked Questions

9
Pelvic pain relief
After one month of taking the drug, my pelvic pain during menstruation disappeared. I occasionally take courses to maintain this benefit.
4
Caused abdominal pain
After a couple of days, I experienced pelvic pain, so I stopped taking it, and the pain went away.
9
Significant pain reduction
Folic acid has notably reduced my pelvic pain and PMS symptoms. My mood is more stable, and my skin, hair, and nails have improved. I recommend it to everyone, including men, for its various benefits.
2
Minimal effectiveness
2 people found this helpful
I bought it to help with my pelvic pain, but I did not notice much effect.
2
Causes discomfort
It's better to take folate instead, as this form induces pelvic pain.
0
Causes stomach pains
My son takes this, but it causes him pelvic pain even when his stomach is full. This didn’t happen with other brands.
We examined the effects of Flower pollen extract with vitamins (Deprox 500®) on chronic pelvic pain compared to Serenoa repens in patients diagnosed with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).

In a randomized controlled trial involving 63 patients, those taking Deprox 500® experienced significant improvements in their symptom scores and overall quality of life.

Notably, patients with hypertension saw an even greater reduction in symptoms. This suggests that Deprox 500® could be a beneficial treatment option for managing pelvic pain.
9
Folic acid nanomedicine alleviates pain
We explored an innovative treatment for chronic bacterial prostatitis (CBP) by creating antibiotic-loaded nanoparticles modified with folic acid. These nanoparticles can effectively target and penetrate the prostate tissues where inflammation and pain occur.

In animal models, the folic acid-modified nanomedicine significantly alleviated pelvic pain and reduced inflammatory markers. This targeted approach enhances antibiotic delivery and improves treatment outcomes for CBP. Although the study showcases promising results, more research is needed to translate these findings to human patients.

References

  1. Zheng J, Hu R, Yang Y, Wang Y, Wang Q, et al. Antibiotic-loaded reactive oxygen species-responsive nanomedicine for effective management of chronic bacterial prostatitis. Acta Biomater. 2022;143:471. 10.1016/j.actbio.2022.02.044
  2. Macchione N, Bernardini P, Piacentini I, Mangiarotti B, Del Nero A. Flower Pollen Extract in Association with Vitamins (Deprox 500®) Versus Serenoa repens in Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Comparative Analysis of Two Different Treatments. Antiinflamm Antiallergy Agents Med Chem. 2019;18:151. 10.2174/1871523018666181128164252
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